Osteoporosis – Cannabis Compound Hardens Bone
Yet another study paper recently been printed that shows how plant based compounds can help to contain the brittle bone disease, osteoporosis. Scientists in the Institute of Medical Sciences, Faculty of Aberdeen, UK have found how a non-psychoactive compound in cannabis, cannabidiol helps you to maintain bone strength.
The endocannabinoid system is a team of cellular receptors which are activated by a group of endogenous lipids as well as elements derived from the cannabis plant. The cannabinoid receptors are engaged in an assortment of physiological processes such as appetite control, discomfort, memory as well as mood. Current research has shown the endocannabinoid system also has a strong impact on bone metabolism, as the receptors are effectively represented on osteoclasts – cells whose major Zatural CBD Gummy Bears (get redirected here) job is to resorb (thin out) bone.
Bone is an energetic, living tissue which is being continuously formed, remodeled as well as shaped in response to both physical and physiological requirements of the body. Bone matrix consists mainly of the macronutrients calcium, phosphate and magnesium and it is the substance that makes up both the dense elements of the bone and also the bone marrow framework. Many individuals still believe that if a person eats foods rich in these minerals then they will avoid developing osteoporosis. Other and epidemiological evidence suggests that this is not necessarily the case.
When it comes to bone health and disease the incorporated processes that control the formation and resorption bone are quite as crucial as the availability of calcium, phosphate and magnesium.
The formation as well as resorbtion of bone matrix is controlled by two main cell types:
One) Osteoblasts are bone cells which are responsible for the development of bone matrix 2) Osteoclasts are altered white blood cells to blame for the resorption of bone tissue.
Osteoblasts
Osteoclasts
These two cell types are controlled by a complicated set of signaling hormones, proteins and cell receptors which react to the ever-changing requirements on bone tissue along with other biological processes. If there are way too many osteoclasts, or if these cells become overactive, they are going to resorb more matrix compared to the osteoblasts are able to produce. A predominance of osteoclast exercise results in the bone becoming less dense – the principal attribute of the medical condition known as osteoporosis.
The Aberdeen researchers have found that cannabidiol binds to a certain cannabinoid receptor on the bone resorbing osteoblast cells. By so doing it prevents these cells from resorbing the bone matrix – thereby helping to avoid further weakening of the bones.