diet as well as Nutrition – Vitamin B6

Vitamin B6 occurs in 3 forms–pyridoxine, pyridoxal, and pyridoxamine. B6 is absorbed in the large intestine. The muscle stores approximately 75 80 % of the vitamin while the live stores about 5 10 %.

B6 is required for transaminations, decarboxylations, dehydratases, side chain cleavage reactions, and ammonia release. The aldehyde group of its works as a Schiff base to respond with the amino groups of amino acids. It basically acts to shuttle nitrogen between compounds.

Functions- The 3 sorts of B6 can all be converted to the coenzyme PLP which aids in transamination and protein metabolism. PLP is important for glycogen degradation; it can also help with the development of the neurotransmitter, serotonin, the nonprotein part of hemoglobin (heme), nucleic acids, and lecithin. Vitamin B6 is essential for the metabolism of tryptophan to niacin.

General Reactions:

· Transaminations These reactions are necessary to recycle as well as reuse nitrogen in the body. They are the first stage in amino acid catabolism as well as the last step in the synthesis of nonessential amino acids. Example: a-ketoglutarate + asparate glutamate + oxaloacetate

· Serine/ Threonine Deamination (Dehydratases) This response supplies the generation of the a-keto acids of serine as well as threonine through oxidative removal of N as ammonia Example: Serine a-keto-serine + NH4+

· Decarboxylation These reactions frequently appear on the neuroactive amines of seratonin, tyramine, histamine, and GABA. They also are crucial in porphyrin synthesis, intermediates in the synthesis of sphingomyelin, lecithin and taurine, and also for the description and desulfuration of cysteine.

· Glycogen Phosphorylase 50 % of all B6 in the body is sure to glycogen phosphorylase though the value is unknown. The reaction is important for meticore reviews canada; Home, recycling of folate and it is as follows:

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